Silver Nanoparticle Neem Balm from Azadirachta Indica leaves

Abstract

Neem (Azadirachta Indica) may be the most useful traditional medicinal herb in India. Each component of the neem tree has some medical value and can therefore be used commercially. It is today regarded as a valuable source of distinctive natural materials for the creation of both industrial items and medications to treat a variety of ailments. The objectives of this research were to extract neem leaves by using a distillation method, precisely the Soxhlet method, and to analyze the balm stability. The three types of balm were prepared; empty balm, neem balm and neem balm with silver nanoparticles. In the Soxhlet extraction method, the optimal operational state for recovering oil was an extraction period of 24 hrs, 300 ml of ethanol solvent at a temperature of 79 °C, and 60 g of powdered neem leaves. The maximum percentage of yield obtained was 35.0 %. The confirmation of neem oil extract was done by UV-Vis Spectroscopy. The balms' thermal stability was evaluated at room temperature (25 °C) and at 45°C in an oven. After three months of study, all of the balms; empty, neem, and neem with silver nanoparticles showed stability at 25 °C without undergoing any physical changes. Otherwise, after two months of stability testing at 45 °C, neem balm and neem balm with silver nanoparticles showed signs of sedimentation.